Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21440816 | 0.84 | ALOX15 (0.45) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL6509907 | 0.78 | ALOX15 (0.67) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL336311 | 0.76 | TSHR (1.00) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Chelidamic Acid SCHEMBL743778 | 0.76 | ALOX15 (0.64) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Chelidamic Acid SCHEMBL794359 | 0.74 | ALOX15 (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL20740850 | 0.74 | ALOX15 (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL744473 | 0.74 | ALOX15 (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| Chelidamic Acid SCHEMBL113302 | 0.74 | ALOX15 (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL137184 | 0.74 | ALOX15 (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL742374 | 0.74 | TSHR (0.61) | ALOX15TSHRHIF1AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027618-A2 | FUNCTIONALIZED CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |