SCHEMBL137184

SCHEMBL137184

O=C(O)c1cc(Br)cc(C(=O)O)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.61
TSHR P16473 2/20 0.61
HIF1A Q16665 1/20 0.61
KDM4E B2RXH2 3/20 0.56
ALDH1A1 P00352 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MCL1 Q07820 6/20 0.50
TDP1 Q9NUW8 2/20 0.50
ACMSD Q8TDX5 1/20 0.50
RXFP1 Q9HBX9 1/20 0.43
PTPN1 P18031 1/20 0.42
POLB P06746 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.41
GPR35 Q9HC97 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28437239 0.97 ALOX15 (0.58) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL29084219 0.89 ALOX15 (0.50) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL31500516 0.88 KDM4E (0.50) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL5918457 0.88 KDM4E (0.50) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL24581474 0.84 ALDH1A1 (0.47) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL1424923 0.84 ALDH1A1 (0.47) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL31336152 0.84 ALDH1A1 (0.47) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL400775 0.84 MAPT (0.50) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL30643514 0.84 MAPT (0.50) ALOX15TSHRHIF1AKDM4EALDH1A1
SCHEMBL1425370 0.83 ALDH1A1 (0.46) ALOX15TSHRHIF1AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878806-B Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2025-02-21 CN claimed
CN-118878806-A Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2024-11-01 CN claimed
CN-117903048-A Synthesis method of 4-bromo-2, 6-diaminopyridine 苏州艾缇克药物化学有限公司 2024-04-19 CN claimed
CN-115745965-B Fluorescent molecule and preparation method and application thereof 华南师范大学 2024-01-30 CN claimed
CN-115745965-A Fluorescent molecule and preparation method and application thereof 华南师范大学 2023-03-07 CN claimed
US-12624391-B2 Cyanine dyes PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2026-05-12 US disclosed
US-20250269043-A1 TARGETED BIFUNCTIONAL DEGRADERS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2025-08-28 US disclosed
CN-118878806-B Zinc pyridine carboxylate complex composite catalyst and preparation method thereof 安徽普碳新材料科技有限公司 2025-02-21 CN disclosed
EP-4493221-A2 TARGETED BIFUNCTIONAL DEGRADERS Yale University (US) 2025-01-22 EP disclosed
CN-119212727-A Targeted bifunctional degradants 耶鲁大学 2024-12-27 CN disclosed
CN-118878808-B Composite catalyst containing zinc pyridine carboxylate complex and preparation method and application thereof 合肥普力先进材料科技有限公司 2024-12-24 CN disclosed
CN-118878807-B Zinc pyridine carboxylate complex composite catalyst 合肥普力先进材料科技有限公司 2024-12-20 CN disclosed
US-20080027042-A1 Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action OHKUBO MITSURU 2008-01-31 US disclosed
US-20080027042-A1 Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action OHKUBO MITSURU 2008-01-31 US disclosed
EP-1848466-A2 MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2007-10-31 EP disclosed
US-20070232572-A1 Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent AVENTIS PHARMA S.A. (FR) 2007-10-04 US disclosed
EP-1813609-A2 NOVEL AMINOPYRIDINE DERIVATIVES HAVING SELECTIVE AURORA-A INHIBITORY EFFECT BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-01 EP disclosed
EP-1813609-A2 NOVEL AMINOPYRIDINE DERIVATIVES HAVING SELECTIVE AURORA-A INHIBITORY EFFECT BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-01 EP disclosed
WO-2006080022-A2 MRI CONTRAST AGENTS FOR DIAGNOSIS AND PROGNOSIS OF TUMORS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2006-08-03 WO disclosed
US-20060106029-A1 Novel aminopyridine derivatives having aurora a selective inhibitory action MSD K.K. (JP) 2006-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250269043-A1 TARGETED BIFUNCTIONAL DEGRADERS SMURF2, SMURF1, MDM2 ALOX15 4328/4885TSHR 1412/4885HIF1A 2106/4885
US-20080027042-A1 Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action AURKA, AURKC, AURKB ALOX15 4825/4885TSHR 2802/4885HIF1A 1600/4885
US-20060106029-A1 Novel aminopyridine derivatives having aurora a selective inhibitory action AURKA, AURKC, AURKB ALOX15 4825/4885TSHR 2802/4885HIF1A 1600/4885
US-20070232572-A1 Chemical derivatives as antitelomerase agents which bind specifically to the G-quadruplex DNA structures and their application as a specific anticancer agent DDX21, DNASE1L3, NTPCR ALOX15 3844/4885TSHR 3032/4885HIF1A 2503/4885
US-12624391-B2 Cyanine dyes POLL, POLR2E, POLR2H ALOX15 3690/4885TSHR 760/4885HIF1A 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.