Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243880 | 0.88 | AGTR2 (0.53) | AGTR2HTR2CPSEN1PSEN2APH1B | |
| SCHEMBL1012557 | 0.86 | HTR2C (0.51) | AGTR2HTR2CELANEHPGDPSEN1 | |
| SCHEMBL1012738 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2ANPEPPSKCNH2 | |
| SCHEMBL17061337 | 0.81 | AGTR2 (0.52) | AGTR2HTR2CPSEN1PSEN2APH1B | |
| SCHEMBL1010265 | 0.78 | FKBP1A (0.46) | AGTR2ELANEHPGDF2KCNH2 | |
| SCHEMBL7652421 | 0.77 | SMN1; SMN2 (0.55) | AGTR2HTR2CPSEN1PSEN2APH1B | |
| SCHEMBL18410317 | 0.76 | HTR2C (0.56) | HTR2CNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL20296331 | 0.76 | HTR2C (0.56) | HTR2CNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8260516 | 0.76 | HTR2C (0.50) | AGTR2HTR2CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL154134 | 0.76 | HTR2C (0.55) | AGTR2HTR2CPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |