Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010265 | 0.89 | FKBP1A (0.46) | SLC6A4SLC6A3KCNH2 | |
| SCHEMBL1011459 | 0.89 | SLC6A4 (0.42) | SLC6A4SLC6A3 | |
| SCHEMBL1015012 | 0.88 | SLC6A4 (0.54) | ALDH1A1SLC6A4SLC6A3KMT2A | |
| SCHEMBL1011495 | 0.88 | SLC6A4 (0.54) | ALDH1A1SLC6A4SLC6A3KMT2A | |
| SCHEMBL1011753 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SLC6A4MEN1KMT2ASIGMAR1 | |
| SCHEMBL1012334 | 0.85 | SLC6A4 (0.44) | SLC6A4SLC6A3KMT2A | |
| SCHEMBL7247464 | 0.83 | SLC6A4 (0.43) | SLC6A4SLC6A3KMT2AKCNH2 | |
| SCHEMBL1012809 | 0.82 | AGTR2 (0.49) | MEN1KMT2ANPEPPSKCNH2 | |
| SCHEMBL7744542 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KMT2AKCNH2PKMNPSR1 | |
| SCHEMBL5466112 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |