Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012738 | 0.89 | ALDH1A1 (0.46) | SLC6A3SLC6A4KCNH2 | |
| SCHEMBL1015012 | 0.86 | SLC6A4 (0.54) | FKBP1ASLC6A3SLC6A4 | |
| SCHEMBL1011495 | 0.86 | SLC6A4 (0.54) | FKBP1ASLC6A3SLC6A4 | |
| SCHEMBL1010837 | 0.86 | FKBP1A (0.47) | FKBP1ASLC6A3F2HPGDTDP1 | |
| SCHEMBL1011459 | 0.85 | SLC6A4 (0.42) | SLC6A3SLC6A4 | |
| SCHEMBL7247464 | 0.84 | SLC6A4 (0.43) | SLC6A3SLC6A4KCNH2 | |
| SCHEMBL1012334 | 0.83 | SLC6A4 (0.44) | SLC6A3SLC6A4 | |
| SCHEMBL1012809 | 0.78 | AGTR2 (0.49) | F2HPGDKCNH2AGTR2ELANE | |
| SCHEMBL7243880 | 0.76 | AGTR2 (0.53) | AGTR2 | |
| SCHEMBL13998413 | 0.75 | HTR2C (0.47) | FKBP1ASLC6A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118674-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TROPINONE MONOCARBOXYLIC ACID DERIVATIVE | NIHON MEDIPHYSICS CO LTD (JP) | 2011-01-05 | — | — | EP | disclosed |