SCHEMBL10128623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14489365	0.96	ACHE (0.38)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL14069775	0.96	ALDH1A1 (0.43)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL1264238	0.96	ACHE (0.41)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL14489460	0.94	ACHE (0.39)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL26288528	0.92	L3MBTL1 (0.43)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL13222609	0.89	ALDH1A1 (0.35)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL10128619	0.89	ACHE (0.41)	ACHETDP1ALDH1A1L3MBTL1MAPT
	SCHEMBL132322	0.89	ALDH1A1 (0.41)	TDP1ALDH1A1L3MBTL1MAPTKDM4E
	SCHEMBL29512028	0.89	ALDH1A1 (0.41)	TDP1ALDH1A1L3MBTL1MAPTKDM4E
	SCHEMBL14181761	0.88	KDM4E (0.32)	ACHETDP1ALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.