SCHEMBL1012912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1013567	0.83	TRPV1 (0.58)	TRPV1NR4A2EGFRALDH1A1MEN1
	SCHEMBL14108441	0.83	TRPV1 (0.61)	TRPV1NPC1NR4A2EGFRALDH1A1
	SCHEMBL13868105	0.74	TRPV1 (1.00)	TRPV1
	SCHEMBL21101485	0.73	ALDH1A1 (0.58)	TRPV1NPC1NR4A2ALDH1A1MEN1
	SCHEMBL12487147	0.73	NPC1 (0.64)	NPC1MKNK1EGFRERBB3ALDH1A1
	SCHEMBL1011814	0.73	TRPV1 (0.48)	TRPV1NPC1EGFRALDH1A1MEN1
	SCHEMBL857502	0.73	NPC1 (0.63)	NPC1MKNK1EGFRERBB3ALDH1A1
	SCHEMBL598102	0.73	NR4A2 (0.58)	TRPV1NPC1NR4A2ALDH1A1MEN1
	SCHEMBL2283204	0.73	NPC1 (0.68)	NPC1MKNK1EGFRERBB3MEN1
	SCHEMBL3952295	0.72	EGFR (0.66)	NPC1MKNK1EGFRERBB3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.