Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658423 | 0.81 | ALDH1A1 (0.53) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL3072828 | 0.81 | ALDH1A1 (0.58) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL29697303 | 0.81 | ALDH1A1 (0.58) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| Hydrochloric Acid SCHEMBL25219076 | 0.79 | ALDH1A1 (0.52) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL21101485 | 0.78 | ALDH1A1 (0.58) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL20206686 | 0.77 | ALDH1A1 (0.53) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL18789747 | 0.77 | MEN1 (0.50) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL12890525 | 0.77 | ALDH1A1 (0.53) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL14805621 | 0.77 | ALDH1A1 (0.53) | NR4A2ALDH1A1MEN1KMT2ACASP1 | |
| SCHEMBL27389314 | 0.77 | MEN1 (0.76) | ALDH1A1MEN1KMT2ACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479803-B2 | Antimalarial compounds | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2022-06-30 | — | — | US | disclosed |
| WO-2020206252-A1 | ANTIMALARIAL COMPOUNDS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| US-8114892-B2 | Methods and compositions for the treatment of Parkinson's Disease | THE MCLEAN HOSPITAL CORPORATION (US) | 2012-02-14 | — | — | US | disclosed |
| US-20090226401-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PARKINSON'S DISEASE | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226401-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PARKINSON'S DISEASE | PARK7, SNCA, RAB7A | NR4A2 4153/4885ALDH1A1 436/4885MEN1 3951/4885 |
| US-12479803-B2 | Antimalarial compounds | H1-3, FPR3, NHERF1 | NR4A2 2183/4885ALDH1A1 3012/4885MEN1 308/4885 |
| US-20220204452-A1 | ANTIMALARIAL COMPOUNDS | H1-3, FPR3, NHERF1 | NR4A2 2183/4885ALDH1A1 3012/4885MEN1 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.