SCHEMBL10129243

SCHEMBL10129243

CC(C)N1CCS(=O)(=O)C1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.45
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10129241 0.86 RAB9A (0.34) RAB9A
SCHEMBL441487 0.84 RAB9A (0.54) RAB9ALMNA
SCHEMBL27014888 0.83 RAB9A (0.44) RAB9ALMNA
SCHEMBL25051819 0.82 RAB9A (0.32) RAB9A
SCHEMBL19523554 0.78
SCHEMBL19544704 0.76 RAB9A (0.34) RAB9A
SCHEMBL10232882 0.76 RAB9A (0.47) RAB9ALMNA
SCHEMBL19263177 0.75 RAB9A (0.50) RAB9ALMNA
SCHEMBL4569231 0.72 RAB9A (0.38) RAB9A
SCHEMBL24624843 0.70 RAB9A (0.55) RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230045509-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CABOTEGRAVIR VIIV HEALTHCARE COMPANY 2023-02-09 US disclosed
US-11084845-B2 C-3 and C-17 modified triterpenoids as HIV-1 inhibitors VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) 2021-08-10 US disclosed
US-20210145824-A1 MODULATORS OF CELLULAR ADHESION NOVARTIS PHARMACEUTICALS CORPORATION (US) 2021-05-20 US disclosed
US-10780102-B2 Triterpenoids with HIV maturation inhibitory activity VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2020-09-22 US disclosed
US-10723733-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2020-07-28 US disclosed
US-20190151336-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY BRISTOL-MYERS SQUIBB COMPANY 2019-05-23 US disclosed
US-20190134022-A1 MODULATORS OF CELLULAR ADHESION SARCODE BIOSCIENCE INC. (US) 2019-05-09 US disclosed
US-10245275-B2 Triterpenoids with HIV maturation inhibitory activity VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2019-04-02 US disclosed
US-20190031709-A1 C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2019-01-31 US disclosed
US-20170340650-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY BRISTOL-MYERS SQUIBB COMPANY 2017-11-30 US disclosed
US-20110124669-A1 Modulators of Cellular Adhesion SARCODE CORPORATION (US) 2011-05-26 US disclosed
US-20110124625-A1 Modulators of Cellular Adhesion SARCODE CORPORATION (US) 2011-05-26 US disclosed
US-20110124625-A1 Modulators of Cellular Adhesion SARCODE CORPORATION (US) 2011-05-26 US disclosed
US-7928122-B2 Modulators of cellular adhesion SARCODE CORPORATION (US) 2011-04-19 US disclosed
US-7790743-B2 Modulators of cellular adhesion SARCODE CORPORATION (US) 2010-09-07 US disclosed
US-7745460-B2 Modulators of cellular adhesion SARCODE CORPORATION (US) 2010-06-29 US disclosed
US-20100093693-A1 MODULATORS OF CELLULAR ADHESION BAUSCH + LOMB IRELAND LIMITED (IE) 2010-04-15 US disclosed
US-20080182839-A1 MODULATORS OF CELLULAR ADHESION SUNESIS PHARMACEUTICALS, INC. (US) 2008-07-31 US disclosed
US-20080176896-A1 Modulators of cellular adhesion BAUSCH + LOMB IRELAND LIMITED (IE) 2008-07-24 US disclosed
US-7314938-B2 Immune and/or inflammatory disorders; autoimmune disorders; disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1); antagonize CD11/CD18 receptors associated with leukocytes. SUNESIS PHARMACEUTICALS, INC. (US) 2008-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210145824-A1 MODULATORS OF CELLULAR ADHESION ITGB1, VCAM1, ITGB8 RAB9A 1028/4885LMNA 1395/4885
US-20080176896-A1 Modulators of cellular adhesion ITGB1, VCAM1, ITGB8 RAB9A 1028/4885LMNA 1395/4885
US-11084845-B2 C-3 and C-17 modified triterpenoids as HIV-1 inhibitors IL17A, BET1, CD4 RAB9A 3126/4885LMNA 2246/4885
US-10780102-B2 Triterpenoids with HIV maturation inhibitory activity CYP51A1, CYP8B1, LSS RAB9A 1593/4885LMNA 2625/4885
US-20190151336-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY CYP51A1, CYP8B1, LSS RAB9A 1593/4885LMNA 2625/4885
US-20100093693-A1 MODULATORS OF CELLULAR ADHESION ITGB1, VCAM1, ITGB8 RAB9A 1028/4885LMNA 1384/4885
US-20110124625-A1 Modulators of Cellular Adhesion ITGB1, VCAM1, ITGB8 RAB9A 1028/4885LMNA 1395/4885
US-10245275-B2 Triterpenoids with HIV maturation inhibitory activity CYP51A1, CYP8B1, LSS RAB9A 1593/4885LMNA 2625/4885
US-20190031709-A1 C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS IL17A, BET1, CD4 RAB9A 3126/4885LMNA 2246/4885
US-10723733-B2 Hepatitis B antiviral agents HAVCR2, SLC10A1, HDGF RAB9A 1809/4885LMNA 2852/4885
US-20110124669-A1 Modulators of Cellular Adhesion ITGB1, VCAM1, ITGB8 RAB9A 1028/4885LMNA 1395/4885
US-20230045509-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING CABOTEGRAVIR CCR5, SAMHD1, THPO RAB9A 1796/4885LMNA 4555/4885
US-20170340650-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY CYP51A1, CYP8B1, LSS RAB9A 1593/4885LMNA 2625/4885
US-20190134022-A1 MODULATORS OF CELLULAR ADHESION ITGB1, VCAM1, ITGB8 RAB9A 1028/4885LMNA 1395/4885
US-20080182839-A1 MODULATORS OF CELLULAR ADHESION ITGB1, VCAM1, ITGB8 RAB9A 1034/4885LMNA 1380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.