SCHEMBL10130968

SCHEMBL10130968

COc1cc(C)cc(Cc2cc(C)cc(CO)c2O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.47
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
HIF1A Q16665 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ERN1 O75460 1/20 0.45
HSPA5 P11021 1/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
PDE4D Q08499 1/20 0.43
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
SHBG P04278 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ACHE P22303 1/20 0.39
ALOX5 P09917 4/20 0.38
CYP2D6 P10635 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130973 1.00 AMY1A (0.47) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL2621002 0.93 ERN1 (0.50) ERN1PDE4APDE4BPDE4CPDE4D
SCHEMBL16888133 0.91 ERN1 (0.52) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL14159051 0.89 SHBG (0.49) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1482608 0.85 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29400422 0.85 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL210506 0.85 AMY1A (0.61) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL18998295 0.84 ERN1 (0.46) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL22222032 0.81 AMY1A (0.49) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL187792 0.79 SHBG (0.52) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170285474-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAMINATE, RESIN PATTERN PRODUCTION METHOD, CURED FILM, AND DISPLAY DEVICE ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-10-05 US disclosed
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed
EP-1645909-B1 Photo-curable resin composition comprising a polyimide, a process for forming a pattern therewith, and a substrate protecting film SHINETSU CHEMICAL CO (JP) 2011-08-24 EP disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
US-7785766-B2 Silphenylene-bearing polymer, photo-curable resin composition, patterning process, and substrate circuit protective film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-08-31 US disclosed
US-7485405-B2 Photo-curable resin composition comprising a polyimide, a process for forming a pattern therewith, and a substrate protecting film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-02-03 US disclosed
US-7476476-B2 Photosensitive resin composition, electronic component using the same, and display unit using the same TORAY INDUSTRIES, INC. (JP) 2009-01-13 US disclosed
US-7455948-B2 Photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2008-11-25 US disclosed
EP-1953183-A2 Silphenylene-bearing polymer, photo-curable resin composition, patterning process, and substrate circuit protective film Shin-Etsu Chemical Co., Ltd. (JP) 2008-08-06 EP disclosed
US-20080182087-A1 SILPHENYLENE-BEARING POLYMER, PHOTO-CURABLE RESIN COMPOSITION, PATTERNING PROCESS, AND SUBSTRATE CIRCUIT PROTECTIVE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-07-31 US disclosed
US-20080075999-A1 Polyelectrolyte Material, Polyelectrolyte Component, Membrane Electrode Composite Body, and Polyelectrolyte Type Fuel Cell TORAY INDUSTRIES, INC. (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD AMY1A 3090/4885CYP2C9 2271/4885CYP2C19 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.