SCHEMBL10130969

SCHEMBL10130969

COc1cc(Cc2cc(C)c(O)c(CO)c2)cc(C)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.74
TNKS2 Q9H2K2 2/20 0.41
PDE4A P27815 2/20 0.41
PDE4B Q07343 2/20 0.41
PDE4C Q08493 2/20 0.41
PDE4D Q08499 2/20 0.41
HMGB1 P09429 1/20 0.40
CXCL12 P48061 1/20 0.40
CALM1 P0DP23 2/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211114 0.88 SHBG (0.58) SHBGTNKS2PDE4APDE4BPDE4C
SCHEMBL9620471 0.88 SHBG (0.52) SHBGTNKS2HMGB1CXCL12CALM1
SCHEMBL10130851 0.86 SHBG (0.56) SHBGTNKS2PDE4APDE4BPDE4C
SCHEMBL14606346 0.86 SHBG (0.56) SHBGTNKS2PDE4APDE4BPDE4C
SCHEMBL30315885 0.86 SHBG (1.00) SHBGHMGB1CXCL12CA2
SCHEMBL209447 0.86 SHBG (1.00) SHBGHMGB1CXCL12CA2
Water SCHEMBL31169663 0.83 SHBG (0.92) SHBGHMGB1CXCL12CA2
SCHEMBL12510599 0.83 TNKS2 (0.49) SHBGTNKS2PDE4APDE4BPDE4C
SCHEMBL14159051 0.79 SHBG (0.49) SHBGTNKS2PDE4APDE4BPDE4C
SCHEMBL829369 0.79 KDM4E (0.52) SHBGTNKS2PDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
US-7476476-B2 Photosensitive resin composition, electronic component using the same, and display unit using the same TORAY INDUSTRIES, INC. (JP) 2009-01-13 US disclosed
US-20080075999-A1 Polyelectrolyte Material, Polyelectrolyte Component, Membrane Electrode Composite Body, and Polyelectrolyte Type Fuel Cell TORAY INDUSTRIES, INC. (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD SHBG 3852/4885TNKS2 2353/4885PDE4A 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.