SCHEMBL10134148

SCHEMBL10134148

O=C1C(=Cc2ccc(N(c3ccccc3)c3ccccc3)cc2)Cc2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.74
MAOA P21397 4/20 0.74
MIF P14174 5/20 0.74
ACHE P22303 3/20 0.64
BCHE P06276 1/20 0.64
CYP19A1 P11511 2/20 0.62
TNF P01375 2/20 0.62
PTGS2 P35354 2/20 0.59
STK17B O94768 1/20 0.58
MAPT P10636 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14020185 1.00 MAOB (0.74) MAOBMAOAMIFACHEBCHE
SCHEMBL10770966 0.90 MAOB (0.73) MAOBMAOAMIFACHEBCHE
SCHEMBL3694617 0.86 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL30462578 0.86 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL30977980 0.86 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL30462577 0.86 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL3700238 0.86 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL2981650 0.86 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL51712 0.85 MAOB (1.00) MAOBMAOAMIFACHEBCHE
SCHEMBL51711 0.85 MAOB (1.00) MAOBMAOAMIFACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed
US-8637860-B2 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORPORATION (JP) 2014-01-28 US disclosed
US-20130181202-A1 PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR PREPARING PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR USING PHOTOELECTRIC CONVERSION DEVICE, PHOTOSENSOR AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-07-18 US disclosed
US-20130122276-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed
US-20130069047-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2013-03-21 US disclosed
US-8378339-B2 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX MAOB 1058/4885MAOA 1477/4885MIF 3574/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO MAOB 724/4885MAOA 1041/4885MIF 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.