SCHEMBL10134646

SCHEMBL10134646

Cc1ccc(C(=O)OC23CC4CC(C2)C(C)C(C4)C3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
HSP90AA1 P07900 2/20 0.43
CKS1B P61024 1/20 0.43
SKP1 P63208 1/20 0.43
SKP2 Q13309 1/20 0.43
RAB9A P51151 3/20 0.42
TDP1 Q9NUW8 1/20 0.41
POLB P06746 2/20 0.39
MAPT P10636 4/20 0.38
NPC1 O15118 1/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
EPHX2 P34913 1/20 0.36
HPGD P15428 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685883 0.88 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL16772260 0.85 ALDH1A1 (0.48) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL17344411 0.80 TDP1 (0.47) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL4373737 0.80 NPSR1 (0.48) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL4362824 0.77 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL24212719 0.76 MEN1 (0.45) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL12500713 0.76 KMT2A (0.45) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL12093413 0.75 NAAA (0.38) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL6368046 0.74 POLB (0.54) ALDH1A1KMT2AMEN1HTTNPSR1
SCHEMBL111835 0.74 MEN1 (0.45) ALDH1A1KMT2AMEN1HTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236842-B2 Salt and process for producing acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
US-20120009519-A1 COMPOUND, RESIN AND PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed
US-20110200936-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
US-20110200935-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
US-20110201823-A1 SALT AND PROCESS FOR PRODUCING ACID GENERATOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
US-20110123926-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-26 US disclosed
US-20110091807-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-20110076617-A1 PHOTORESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-31 US disclosed
US-20100330497-A1 CHEMICALLY AMPLIFIED PHOTORESIST COMPOSITION AND METHOD FOR FORMING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200935-A1 PHOTORESIST COMPOSITION C1R, F12, C1S ALDH1A1 2022/4885KMT2A 2752/4885MEN1 2992/4885
US-20120009519-A1 COMPOUND, RESIN AND PHOTORESIST COMPOSITION C1R, C1S, C9 ALDH1A1 2064/4885KMT2A 869/4885MEN1 1501/4885
US-20110091807-A1 PHOTORESIST COMPOSITION H1-0, H1-2, H1-3 ALDH1A1 1807/4885KMT2A 599/4885MEN1 2450/4885
US-20110201823-A1 SALT AND PROCESS FOR PRODUCING ACID GENERATOR FGFR1, MTX1, RER1 ALDH1A1 2214/4885KMT2A 1055/4885MEN1 14/4885
US-20110200936-A1 SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME RER1, AFF1, FRG1 ALDH1A1 2966/4885KMT2A 1523/4885MEN1 536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.