Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 10/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | PRKACA | P17612 | 4/20 | 0.41 |
| ▸ | PRKX | P51817 | 2/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137258 | 0.86 | KDM4E (0.38) | ROCK1ROCK2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12249821 | 0.82 | ENPP2 (0.41) | CHKAKDM4EALDH1A1RAB9ABCHE | |
| SCHEMBL13561376 | 0.81 | CHKA (0.53) | CHKAPRKCIKDM4EALDH1A1RAB9A | |
| SCHEMBL25459998 | 0.75 | PRKCI (0.55) | CYP3A4CHKAPRKCIKDM4EALDH1A1 | |
| SCHEMBL12530002 | 0.74 | ENPP2 (0.46) | ROCK1ROCK2CHKAPRKCIKDM4E | |
| SCHEMBL1108034 | 0.73 | ALDH1A1 (0.66) | ROCK1ROCK2PRKACAPRKXGSK3A | |
| Hydrochloric Acid SCHEMBL7166354 | 0.73 | ALDH1A1 (0.66) | ROCK1ROCK2PRKACAPRKXGSK3A | |
| SCHEMBL25459980 | 0.72 | KDM4E (0.45) | CHKAPRKCIKDM4EALDH1A1RAB9A | |
| SCHEMBL25460377 | 0.72 | KDM4E (0.65) | CHKAPRKCIKDM4EALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL28933331 | 0.72 | FOLH1 (0.45) | ROCK1ROCK2PRKACAPRKXGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-16 | — | — | US | disclosed |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | ROCK1 3630/4885ROCK2 3385/4885CYP3A4 922/4885 |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | ROCK1 3630/4885ROCK2 3385/4885CYP3A4 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.