SCHEMBL101380

SCHEMBL101380

CSC(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHCY P23526 8/20 0.62
PRMT5 O14744 1/20 0.61
WDR77 Q9BQA1 1/20 0.61
NADK O95544 1/20 0.60
KMT2A Q03164 2/20 0.60
ADORA3 P0DMS8 2/20 0.60
ADORA2A P29274 2/20 0.60
ADORA2B P29275 2/20 0.60
ADORA1 P30542 2/20 0.60
HSP90B1 P14625 2/20 0.60
TSHR P16473 1/20 0.60
LMNA P02545 1/20 0.60
THRB P10828 1/20 0.60
BLM P54132 1/20 0.60
HSP90AA1 P07900 1/20 0.60
DPP4 P27487 1/20 0.60
MEN1 O00255 1/20 0.60
SLC28A1 O00337 1/20 0.60
MAP3K7 O43318 1/20 0.60
SLC28A2 O43868 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6894498 0.89 AHCY (0.59) AHCYPRMT5WDR77NADKKMT2A
SCHEMBL2118345 0.89 AHCY (0.61) AHCYPRMT5WDR77NADKKMT2A
SCHEMBL3488655 0.89 AHCY (0.62) AHCYNADKKMT2AADORA3ADORA2A
SCHEMBL397800 0.88 AHCY (0.68) AHCYPRMT5WDR77KMT2AADORA3
SCHEMBL31680251 0.88 AHCY (0.68) AHCYPRMT5WDR77KMT2AADORA3
SCHEMBL3515650 0.87 PRMT5 (0.50) AHCYPRMT5WDR77NADKKMT2A
SCHEMBL21413837 0.87 PRMT5 (0.64) AHCYPRMT5WDR77KMT2AADORA3
SCHEMBL16300875 0.87 PRMT5 (0.64) AHCYPRMT5WDR77KMT2AADORA3
SCHEMBL22326787 0.87 PRMT5 (0.64) AHCYPRMT5WDR77KMT2AADORA3
SCHEMBL22326785 0.87 PRMT5 (0.64) AHCYPRMT5WDR77KMT2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144829-A1 SYNBIOTIC COMPOSITION, METABOLITES, AND METHOD OF PREVENTING AND TREATING OBESITY-RELATED DISEASE Hsu, Cheng-Chih (TW) 2026-05-28 US claimed
US-20260051387-A1 METABOLOMIC ANALYSIS OF PERITONEAL DIALYSIS EFFLUENT FRESENIUS MEDICAL CARE HOLDINGS, INC. (US) 2026-02-19 US claimed
US-20250341515-A1 METABOLOMIC BIOMARKERS FOR ACUTE KIDNEY INJURY, ASSAYS, COMPOSITIONS AND METHODS OF USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2025-11-06 US claimed
EP-4597111-A1 USE OF METABOLIC MARKER FOR DIAGNOSIS OF LUNG CANCER STAGING AND KIT Harbin Metanotitia Inc. (CN) 2025-08-06 EP claimed
WO-2025085615-A1 METHODS TO RAPIDLY DETECT METHYLTHIOADENOSINE AND RELATED METABOLITES DIRECTLY FROM PATIENT SAMPLES TO IDENTIFY 9P21 LOSS CANCERS AND TREATMENT STRATEGIES FOR PATIENTS BAYLOR COLLEGE OF MEDICINE (US) 2025-04-24 WO claimed
WO-2024230650-A1 SYNBIOTIC COMPOSITION, METABOLITE AND USE THEREOF IN PREVENTION AND TREATMENT OF OBESITY-RELATED DISEASES 徐丞志 2024-11-14 WO claimed
WO-2024152730-A1 BIOMARKERS FOR IDENTIFYING INFREQUENT GOUT FLARES AND FREQUENT GOUT FLARES AND USE THEREOF 苏州艾麦锶生命科技有限公司 2024-07-25 WO claimed
US-12018299-B2 Methods and kits for quantifying adenosine-containing molecules SEVIVO LLC (US) 2024-06-25 US claimed
CN-116381072-B Biomarker for identifying sporadic gout and frequent gout and application thereof 苏州艾麦锶生命科技有限公司 2024-05-31 CN claimed
CN-118011003-A Biomarker composition for diagnosing gastric cancer and application thereof 哈尔滨脉图精准技术有限公司 2024-05-10 CN claimed
EP-0974362-A1 DRUGS CONTAINING ENZYME INHIBITORS AS THE ACTIVE INGREDIENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2000-01-26 EP claimed
EP-0869183-A1 Genetic control of ethylene biosynthesis in plants AGRITOPE, INC. (US) 1998-10-07 EP claimed
EP-0505440-B1 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS AGRITOPE INC (US) 1998-07-22 EP claimed
US-5589623-A TRANSFORMING PLANT CELLS WITH A VECTOR CONTAINING A DNA SEQUENCE ENCODING AN S-ADENOSYLMETHIONINE HYDROLASE ENZYME AGRITOPE, INC. (US) 1996-12-31 US claimed
EP-0693127-A1 USE OF TOMATO E8-DERIVED PROMOTERS TO EXPRESS HETEROLOGOUS GENES, E.G. S-ADENOSYLMETHIONINE HYDROLASE, IN RIPENING FRUIT EPITOPE, INC. (US) 1996-01-24 EP claimed
US-5416250-A Genetic control of ethylene biosynthesis in plants using S-adenosylmethionine hydrolase AGRITOPE, INC. (US) 1995-05-16 US claimed
WO-1994024294-A1 USE OF TOMATO E8-DERIVED PROMOTERS TO EXPRESS HETEROLOGOUS GENES, E.G. S-ADENOSYLMETHIONINE HYDROLASE, IN RIPENING FRUIT EPITOPE, INC. (US) 1994-10-27 WO claimed
EP-0505440-A4 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS 1992-11-19 EP claimed
EP-0505440-A1 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS AGRITOPE, INC. (US) 1992-09-30 EP claimed
WO-1991009112-A1 GENETIC CONTROL OF ETHYLENE BIOSYNTHESIS IN PLANTS AGRITOPE, INC. (US) 1991-06-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144829-A1 SYNBIOTIC COMPOSITION, METABOLITES, AND METHOD OF PREVENTING AND TREATING OBESITY-RELATED DISEASE MLN, COMT, MLEC AHCY 77/4885PRMT5 158/4885WDR77 1389/4885
US-20260051387-A1 METABOLOMIC ANALYSIS OF PERITONEAL DIALYSIS EFFLUENT SLC43A1, SLC14A1, SLC1A5 AHCY 183/4885PRMT5 2598/4885WDR77 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.