Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716434 | 0.83 | LMNA (0.70) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL6559600 | 0.83 | ALDH1A1 (0.67) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL2729695 | 0.83 | ALDH1A1 (0.63) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL9680671 | 0.82 | ALDH1A1 (0.58) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL10139198 | 0.82 | MAPT (0.62) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL9681150 | 0.82 | LMNA (0.60) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL28288806 | 0.81 | KMT2A (0.71) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL19790196 | 0.80 | KDM4E (0.59) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL3125877 | 0.80 | TSHR (0.55) | LMNAHCAR3ALDH1A1HTTKDM4E | |
| SCHEMBL26621578 | 0.79 | HCAR3 (0.56) | LMNAHCAR3ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |