Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096091 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11MMP9SMN1; SMN2ALDH1A1 | |
| SCHEMBL4113212 | 0.82 | CYP4F2 (0.76) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL184666 | 0.82 | CYP4F2 (0.56) | CYP4F2CYP4A11MMP9SMN1; SMN2ALDH1A1 | |
| SCHEMBL22664337 | 0.82 | CA2 (0.58) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL257153 | 0.82 | MMP9 (0.57) | CYP4F2CYP4A11MMP9SMN1; SMN2ALDH1A1 | |
| SCHEMBL23665692 | 0.81 | CYP4F2 (0.54) | CYP4F2CYP4A11MMP9SMN1; SMN2ALDH1A1 | |
| SCHEMBL24032613 | 0.81 | SMN1; SMN2 (0.59) | CYP4F2CYP4A11MMP9SMN1; SMN2ALDH1A1 | |
| SCHEMBL175501 | 0.78 | CYP4F2 (0.60) | CYP4F2CYP4A11MMP9SMN1; SMN2ALDH1A1 | |
| SCHEMBL12440455 | 0.78 | ALDH1A1 (0.60) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL829305 | 0.77 | CYP4F2 (0.63) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |