Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487379 | 0.79 | LMNA (0.72) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL5487375 | 0.79 | LMNA (0.72) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6180605 | 0.78 | KMT2A (0.68) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL1151817 | 0.77 | LMNA (0.58) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL6596304 | 0.77 | LMNA (0.58) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL9530000 | 0.77 | LMNA (0.58) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL1151821 | 0.77 | LMNA (0.58) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7365405 | 0.76 | LMNA (0.68) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7304629 | 0.76 | S1PR1 (0.67) | SMN1; SMN2KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7365408 | 0.76 | LMNA (0.68) | SMN1; SMN2KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | BIOMARIN PHARMACEUTICAL INC. | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100609-A1 | N-LINKED GLYCAN BIOSYNTHESIS MODULATORS | ENGASE, GALNT1, GALNT13 | SMN1; SMN2 4780/4885KDM4E 3708/4885LMNA 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.