Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147479 | 0.84 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1KMT2AHPGDDPP4 | |
| SCHEMBL14227522 | 0.81 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KMT2AKDM4EBCHE | |
| SCHEMBL777188 | 0.73 | KMT2A (0.44) | L3MBTL1KMT2ABCHEACHEIDO1 | |
| SCHEMBL422010 | 0.72 | USP2 (0.51) | L3MBTL1ALDH1A1KMT2AIDO1LOXL2 | |
| SCHEMBL24429451 | 0.72 | KMT2A (0.49) | L3MBTL1ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL351585 | 0.72 | HPGD (0.41) | ALDH1A1KMT2AHPGDDPP4KDM4E | |
| SCHEMBL775451 | 0.71 | LMNA (0.44) | L3MBTL1KMT2ABCHEACHEIDO1 | |
| SCHEMBL351784 | 0.71 | MAPT (0.44) | L3MBTL1ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL9421733 | 0.70 | FAAH (0.62) | L3MBTL1KMT2ABCHEACHEKCNA5 | |
| SCHEMBL10146079 | 0.69 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, TRPV1 | L3MBTL1 4584/4885ALDH1A1 2844/4885KMT2A 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.