Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014802 | 0.93 | TSHR (0.44) | TSHRKEAP1NFE2L2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3983490 | 0.92 | TSHR (0.42) | TSHRKEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL7752178 | 0.86 | DTYMK (0.46) | TSHRKEAP1NFE2L2NPC1RAB9A | |
| SCHEMBL1790306 | 0.85 | TSHR (0.49) | TSHRDTYMKTDP1ALDH1A1VCAM1 | |
| SCHEMBL7744988 | 0.85 | CA12 (0.46) | NPC1RAB9ATDP1ATMESPL1 | |
| SCHEMBL31094840 | 0.85 | CA12 (0.46) | NPC1RAB9ATDP1ATMESPL1 | |
| SCHEMBL1020420 | 0.84 | DTYMK (0.46) | TSHRDTYMKTDP1ATMESPL1 | |
| SCHEMBL13948939 | 0.84 | DTYMK (0.50) | TSHRDTYMKTDP1ATMESPL1 | |
| SCHEMBL7749601 | 0.84 | ALDH1A1 (0.53) | TSHRDTYMKALDH1A1VCAM1CYP3A4 | |
| Benzoic Acid SCHEMBL25317758 | 0.84 | VCAM1 (0.49) | TSHRNPC1RAB9ATDP1AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294721-A | Reacting a halonitrobenzene and a pyridinium salt | ABBOTT LABORATORIES (US) | 1994-03-15 | — | — | US | claimed |
| US-20250223299-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. | 2025-07-10 | — | — | US | disclosed |
| US-12297207-B2 | Maytansinoid derivatives, conjugates thereof, and methods of use | REGENERON PHARMACEUTICALS, INC. (US) | 2025-05-13 | — | — | US | disclosed |
| CN-115645543-A | Maytansinoid derivatives, conjugates thereof, and methods of use | 里珍纳龙药品有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20220259225-A1 | Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use | REGENERON PHARMACEUTICALS, INC. | 2022-08-18 | — | — | US | disclosed |
| US-20200385402-A1 | Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use | REGENERON PHARMACEUTICALS, INC. | 2020-12-10 | — | — | US | disclosed |
| EP-3273998-B1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMA (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-3273998-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | Regeneron Pharmaceuticals, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| US-20160375147-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. | 2016-12-29 | — | — | US | disclosed |
| WO-2016160615-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2016-10-06 | — | — | WO | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0655997-B1 | PYRIDINIUM INTERMEDIATES AND THE PROCESS FOR PREPARING THE SAME | ABBOTT LAB (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0655997-A1 | PYRIDINIUM INTERMEDIATES AND THE PROCESS FOR PREPARING THE SAME. | ABBOTT LAB (US) | 1995-06-07 | — | — | EP | disclosed |
| EP-0655997-A4 | PYRIDINIUM INTERMEDIATES AND THE PROCESS FOR PREPARING THE SAME. | ABBOTT LAB (US) | 1995-02-10 | — | — | EP | disclosed |
| EP-0610384-A4 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0610384-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1994-08-17 | — | — | EP | disclosed |
| US-5294721-A | Reacting a halonitrobenzene and a pyridinium salt | ABBOTT LABORATORIES (US) | 1994-03-15 | — | — | US | disclosed |
| WO-1994004502-A1 | PYRIDINIUM INTERMEDIATES AND THE PROCESS FOR PREPARING THE SAME | ABBOTT LABORATORIES (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993009077-A2 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LABORATORIES (US) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160375147-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | SLC10A1, HNMT, OGFR | TSHR 1150/4885KEAP1 968/4885NFE2L2 1774/4885 |
| US-20250223299-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | SLC10A1, HNMT, OGFR | TSHR 1150/4885KEAP1 968/4885NFE2L2 1774/4885 |
| US-20200385402-A1 | Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use | SLC10A1, HNMT, OGFR | TSHR 1150/4885KEAP1 968/4885NFE2L2 1774/4885 |
| US-12297207-B2 | Maytansinoid derivatives, conjugates thereof, and methods of use | SLC10A1, HNMT, OGFR | TSHR 1150/4885KEAP1 968/4885NFE2L2 1774/4885 |
| US-20220259225-A1 | Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use | SLC10A1, HNMT, OGFR | TSHR 1150/4885KEAP1 968/4885NFE2L2 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.