Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 5/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753968 | 0.83 | RAB9A (0.55) | RAB9APOLBMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL6370237 | 0.80 | RAB9A (0.68) | RAB9APOLBMEN1KMT2AHDAC2 | |
| Hydrochloric Acid SCHEMBL9025468 | 0.77 | CHRNA7 (0.51) | RAB9APOLBMEN1KMT2ANPC1 | |
| SCHEMBL22397972 | 0.76 | DYRK1A (0.50) | RAB9AMEN1KMT2ANPC1CLK1 | |
| SCHEMBL4154762 | 0.76 | MEN1 (0.48) | RAB9APOLBMEN1KMT2AITGB3 | |
| SCHEMBL447565 | 0.75 | HDAC1 (0.49) | RAB9AMEN1KMT2ANPC1CLK1 | |
| SCHEMBL2897390 | 0.74 | BCL2L1 (0.59) | RAB9AMEN1KMT2ANPC1CLK1 | |
| SCHEMBL29742282 | 0.74 | BCL2L1 (0.59) | RAB9AMEN1KMT2ANPC1CLK1 | |
| SCHEMBL4253298 | 0.73 | HDAC1 (0.45) | RAB9APOLBMEN1KMT2AITGB3 | |
| SCHEMBL19756728 | 0.72 | MEN1 (0.49) | RAB9AMEN1KMT2ANPC1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | RAB9A 1660/4885POLB 3114/4885MEN1 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.