Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336528 | 0.93 | DUT (0.33) | DUT | |
| SCHEMBL16928562 | 0.88 | TSHR (0.42) | TSHRSMN1; SMN2DUT | |
| SCHEMBL9425765 | 0.82 | DUT (0.37) | TSHRSMN1; SMN2DUT | |
| SCHEMBL8151339 | 0.81 | TSHR (0.44) | TSHRSMN1; SMN2DUT | |
| SCHEMBL10181980 | 0.79 | — | — | |
| SCHEMBL1804485 | 0.77 | DUT (0.32) | TSHRDUT | |
| SCHEMBL5847954 | 0.76 | DUT (0.33) | TSHRSMN1; SMN2DUT | |
| SCHEMBL5536879 | 0.75 | DUT (0.34) | DUT | |
| SCHEMBL5528968 | 0.75 | DUT (0.34) | DUT | |
| SCHEMBL29864586 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140106367-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-04-17 | — | — | US | disclosed |
| US-8530459-B2 | Swallowtail motifs for imparting water solubility to porphyrinic compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-09-10 | — | — | US | disclosed |
| US-20120245508-A1 | SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-09-27 | — | — | US | disclosed |
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082621-A1 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | ALK, ACVRL1, ACVR1 | TSHR 2050/4885SMN1; SMN2 2418/4885DUT 4734/4885 |
| US-20120245508-A1 | SYNTHESIS OF CHLORINS AND PHORBINES WITH ENHANCED RED SPECTRAL FEATURES | CRY1, CRY2, QDPR | TSHR 1796/4885SMN1; SMN2 4882/4885DUT 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.