Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962658 | 0.70 | L3MBTL1 (0.45) | MAPTCFTRRAB9AL3MBTL1PTPN7 | |
| SCHEMBL344681 | 0.70 | MAPT (0.48) | MAPTCFTRKDM4EALDH1A1HPGD | |
| SCHEMBL5316664 | 0.70 | DUSP3 (0.48) | MAPTCFTRRAB9AL3MBTL1PTPN7 | |
| SCHEMBL320173 | 0.68 | CYP2C19 (0.50) | MAPTCFTRKDM4EALDH1A1HPGD | |
| SCHEMBL29617695 | 0.67 | CFTR (0.50) | MAPTCFTRRAB9AL3MBTL1KDM4E | |
| SCHEMBL4070406 | 0.67 | CFTR (0.62) | MAPTCFTRESRRAKDM4EALDH1A1 | |
| SCHEMBL4638408 | 0.67 | CFTR (0.50) | MAPTCFTRRAB9AL3MBTL1KDM4E | |
| SCHEMBL345774 | 0.65 | KDM4E (0.58) | CFTRKDM4EALDH1A1HPGDCYP2C19 | |
| SCHEMBL8116935 | 0.64 | SLC9A1 (0.50) | MAPTCFTRCNR2CNR1 | |
| SCHEMBL10148475 | 0.64 | PTGS2 (0.35) | MAPTCFTRRAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004706-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |