SCHEMBL10150841

SCHEMBL10150841

O=C(OCC12CC3CC(CC(CO)(C3)C1)C2)C(F)(F)S(=O)(=O)O/N=C(/c1ccccc1)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.32
SCN9A Q15858 2/20 0.32
PRSS1 P07477 1/20 0.30
TPSAB1 Q15661 1/20 0.30
TPSD1 Q9BZJ3 1/20 0.30
TPSG1 Q9NRR2 1/20 0.30
DPP8 Q6V1X1 1/20 0.30
DPP9 Q86TI2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10150837 0.91 SCN9A (0.37) P2RX7SCN9ADPP8DPP9
SCHEMBL10150823 0.91 P2RX7 (0.38) P2RX7SCN9A
SCHEMBL14839328 0.81 SCN9A (0.37) P2RX7SCN9A
SCHEMBL14839337 0.78 SCN9A (0.32) SCN9A
SCHEMBL547314 0.76 SCN9A (0.34) P2RX7SCN9APRSS1TPSAB1TPSD1
SCHEMBL18232679 0.75 SCN9A (0.36) SCN9APRSS1TPSAB1TPSD1TPSG1
SCHEMBL785675 0.74 SCN9A (0.36) SCN9APRSS1TPSAB1TPSD1TPSG1
SCHEMBL10150830 0.73 TDP1 (0.38)
SCHEMBL10150824 0.73 HDAC6 (0.35)
SCHEMBL10150820 0.72 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173350-B2 Oxime compound and resist composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-08 US disclosed
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021847-A1 Oxime Compound and Resist Composition Containing the Same CYC1, UQCRB, CBR1 P2RX7 4485/4885SCN9A 1835/4885PRSS1 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.