Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18198913 | 0.82 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL1010858 | 0.78 | NPSR1 (0.33) | ALDH1A1 | |
| SCHEMBL12691979 | 0.74 | RAPGEF4 (0.30) | — | |
| SCHEMBL10029426 | 0.74 | ALDH1A1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL12691982 | 0.73 | — | — | |
| SCHEMBL17532970 | 0.72 | ALDH1A1 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL7760842 | 0.72 | ALDH1A1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL12852201 | 0.71 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL12852204 | 0.71 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL12852210 | 0.71 | KDM4E (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315910-A | Synthetic method of N-heterocyclic carbene allyl palladium chloride compound | 安徽敦茂新材料科技有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114315910-A | Synthetic method of N-heterocyclic carbene allyl palladium chloride compound | 安徽敦茂新材料科技有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-2015115938-A1 | RUTHENIUM CATALYST FOR METATHESIS POLYMERIZATION OF DICYCLOPENTADIENE IN FORM OF CATIONIC COMPLEX, AND PREPARATION METHOD THEREOF | Открытое акционерное общество "Нефтяная компания "Роснефть" | 2015-08-06 | — | — | WO | disclosed |
| WO-2015115937-A1 | DICYCLOPENTADIENE METATHESIS POLYMERIZATION CATALYST IN THE FORM OF A RUTHENIUM COMPLEX AND METHOD FOR PRODUCING SAME | Открытое акционерное общество "Нефтяная компания "Роснефть" | 2015-08-06 | — | — | WO | disclosed |
| US-20120241250-A1 | Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers | EAKIN GEORGE R (US) | 2012-09-27 | — | — | US | disclosed |
| EP-1372844-B1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INST OF TECHN (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-1372844-A4 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INST OF TECHN (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6838489-B2 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | CYMETECH, LLC (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1372844-A1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | California Institute of Technology (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003097562-A2 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-11-27 | — | — | WO | disclosed |
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | STERLING JA, L.C. | 2003-07-31 | — | — | US | disclosed |
| US-20030083445-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | STERLING JA, L.C. | 2003-05-01 | — | — | US | disclosed |
| WO-2002076613-A1 | HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144437-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | NQO1, NIT2, ALOX5 | KDM4E 4592/4885ALDH1A1 1236/4885 |
| US-20030083445-A1 | High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor | NQO1, NIT2, ALOX5 | KDM4E 4592/4885ALDH1A1 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.