SCHEMBL10156018

SCHEMBL10156018

CCC(C)(CC(C)C(=O)OC)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
DGAT1 O75907 1/20 0.32
ESRRB O95718 1/20 0.32
CA14 Q9ULX7 2/20 0.31
PRKCA P17252 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16811778 0.90 MMP8 (0.35) MMP8CA1CA2USP2LMNA
SCHEMBL11913584 0.90 MMP8 (0.35) MMP8CA1CA2USP2LMNA
SCHEMBL19420344 0.90 MMP8 (0.35) MMP8CA1CA2PRKCA
SCHEMBL12363480 0.90 MMP8 (0.35) MMP8CA1CA2USP2LMNA
SCHEMBL25560345 0.89 MMP8 (0.44) MMP8SMN1; SMN2LMNAHPGD
SCHEMBL13645728 0.87 CA1 (0.35) MMP8CA1CA2SMN1; SMN2ESRRB
SCHEMBL15711664 0.85 MMP8 (0.35) MMP8DGAT1
SCHEMBL13246446 0.85 MMP8 (0.35) MMP8DGAT1
SCHEMBL2609283 0.84 MMP8 (0.34) MMP8PRKCA
SCHEMBL13748355 0.83 MMP8 (0.34) MMP8DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546261-B2 Stabilizing of organic material with amino-triazine based mannich-compounds BOREALIS AG (AT) 2017-01-17 US disclosed
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds BOREALIS AG (AT) 2014-08-21 US disclosed
US-8277695-B2 Reversibly thermochromic compositions BASF SE (DE) 2012-10-02 US disclosed
US-8119778-B2 Reversibly thermochromic compositions BASF SE (DE) 2012-02-21 US disclosed
US-20110256312-A1 OPTICAL FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110180767-A1 Reversibly thermochromic compositions CIBA CORPORATION 2011-07-28 US disclosed
US-20110092632-A1 POROUS INORGANIC MATERIALS CONTAINING POLYMER ADDITIVES BRAND FABIEN JEAN 2011-04-21 US disclosed
US-7820744-B2 Stabilizer mixtures CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-26 US disclosed
US-20100234494-A1 Reversibly thermochromic compositions CIBA CORPORATION 2010-09-16 US disclosed
US-7687554-B2 Water based concentrated product forms of light stabilizers made by a heterophase polymerization technique CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-03-30 US disclosed
US-20100048774-A1 STABILIZER MIXTURES GUGUMUS FRANCOIS 2010-02-25 US disclosed
US-20090312464-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-12-17 US disclosed
US-7628936-B2 Mixture of steric hindred amine compound with magnesium and zinc salt; photostability; heat and oxidation resistance; for polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-12-08 US disclosed
US-20090111917-A1 Stabilized articles BONORA MICHELA 2009-04-30 US disclosed
US-20090105379-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-23 US disclosed
US-20090093572-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-09 US disclosed
US-20080058459-A1 Porous Inorganic Materials Containing Polymer Additives CIBA CORP. 2008-03-06 US disclosed
US-7332105-B2 Synergistic UV absorber combination CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-02-19 US disclosed
US-20070207298-A1 Optical film, anti-reflection film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070135537-A1 Agricultural articles BONORA MICHAEL 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234494-A1 Reversibly thermochromic compositions CRY1, REL, CRY2 MMP8 4768/4885CA1 577/4885CA2 141/4885
US-20140235766-A1 Stabilizing of Organic Material with Amino-Triazine Based Mannich-Compounds PCNA, SOD1, UBE2M MMP8 3308/4885CA1 3991/4885CA2 4462/4885
US-20110180767-A1 Reversibly thermochromic compositions C1R, C3AR1, C9 MMP8 4814/4885CA1 241/4885CA2 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.