Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862935 | 0.87 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL10158281 | 0.81 | MAPT (0.50) | CSNK2A1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11868776 | 0.75 | MCHR1 (0.49) | MAPTALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL7928280 | 0.73 | MCHR1 (0.58) | CSNK2A1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL22787328 | 0.72 | MAPT (0.44) | MAPTALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL3784534 | 0.71 | MCHR1 (0.49) | CSNK2A1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL9410520 | 0.71 | CLCN2 (0.38) | CSNK2A1ALDH1A1POLBHTTL3MBTL1 | |
| SCHEMBL31569145 | 0.71 | CTRC (0.38) | MAPTALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL7849660 | 0.70 | IKBKB (0.46) | CSNK2A1MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL11794509 | 0.69 | HSD17B10 (0.46) | MAPTALDH1A1KDM4EPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220076-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INT (DE) | 2012-01-18 | — | — | EP | disclosed |