Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158713 | 0.84 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL10158702 | 0.81 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL10158719 | 0.79 | TLR2 (0.40) | CES2 | |
| SCHEMBL10158689 | 0.77 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL29012515 | 0.76 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL13445921 | 0.76 | CES2 (0.34) | CES2 | |
| SCHEMBL10158711 | 0.75 | LMNA (0.32) | ALDH1A1 | |
| SCHEMBL10158708 | 0.75 | TSHR (0.31) | ALDH1A1 | |
| SCHEMBL10158716 | 0.74 | AKT1 (0.31) | — | |
| SCHEMBL1470162 | 0.74 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130195954-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338492-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8334324-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20120107365-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110152305-A1 | FILMS AND PARTICLES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-7671095-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080075718-A1 | Films and Particles | THE TRUSTEES OF THE BOSTON UNIVERSITY | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152305-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885CES2 105/4885 |
| US-20130195954-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885CES2 105/4885 |
| US-20080075718-A1 | Films and Particles | APOB, PGF, ACTB | ALDH1A1 2505/4885CES2 105/4885 |
| US-20120107365-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885CES2 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.