Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 4/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830120 | 0.95 | ALDH1A1 (0.43) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10158740 | 0.91 | ALDH1A1 (0.48) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10158751 | 0.90 | ALDH1A1 (0.57) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL12564600 | 0.90 | ALDH1A1 (0.61) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10158747 | 0.89 | ALDH1A1 (0.46) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10158718 | 0.88 | ALDH1A1 (0.48) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL18236019 | 0.86 | ALDH1A1 (0.43) | ALDH1A1LMNAPRKCAPRKCEPRKCQ | |
| SCHEMBL10158672 | 0.82 | ENPP2 (0.40) | ALDH1A1PRKCALPAR3LPAR1LPAR2 | |
| SCHEMBL26695782 | 0.82 | LMNA (0.35) | ALDH1A1LMNAPRKCA | |
| SCHEMBL13764220 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNALPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160169864-A1 | FIBER COATED NANOPORES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
| US-20130195954-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2013-08-01 | — | — | US | disclosed |
| US-8338492-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8334324-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-12-18 | — | — | US | disclosed |
| US-20120107365-A1 | FILMS AND PARTICLES | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110152305-A1 | FILMS AND PARTICLES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-7671095-B2 | Films and particles | THE TRUSTEES OF THE BOSTON UNIVERSITY (US) | 2010-03-02 | — | — | US | disclosed |
| US-20080075718-A1 | Films and Particles | THE TRUSTEES OF THE BOSTON UNIVERSITY | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152305-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885LMNA 220/4885PRKCA 2951/4885 |
| US-20130195954-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885LMNA 220/4885PRKCA 2951/4885 |
| US-20080075718-A1 | Films and Particles | APOB, PGF, ACTB | ALDH1A1 2505/4885LMNA 220/4885PRKCA 2951/4885 |
| US-20120107365-A1 | FILMS AND PARTICLES | APOB, PGF, ACTB | ALDH1A1 2505/4885LMNA 220/4885PRKCA 2951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.