SCHEMBL346687

SCHEMBL346687

C=C(C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.59
NAALAD2 Q9Y3Q0 1/20 0.56
ACE P12821 9/20 0.54
MME P08473 6/20 0.54
CPA1 P15085 1/20 0.54
ACE2 Q9BYF1 1/20 0.54
TGFBR1 P36897 1/20 0.54
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
SLC7A5 Q01650 1/20 0.50
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021425 1.00 FOLH1 (0.59) FOLH1NAALAD2ACEMMECPA1
SCHEMBL8393441 0.88 FOLH1 (0.62) FOLH1NAALAD2ACEMMECPA1
SCHEMBL14213197 0.88 FOLH1 (0.62) FOLH1NAALAD2ACEMMECPA1
SCHEMBL8393434 0.88 FOLH1 (0.62) FOLH1NAALAD2ACEMMECPA1
SCHEMBL346221 0.88 TGFBR1 (0.57) NAALAD2ACEMMECPA1ACE2
SCHEMBL2258793 0.88 TGFBR1 (0.57) NAALAD2ACEMMECPA1ACE2
SCHEMBL718780 0.87 ACE (0.51) FOLH1ACECA1SLC7A5MMP9
SCHEMBL23859819 0.85 NPSR1 (0.56)
SCHEMBL21117405 0.85 MMP9 (0.55) FOLH1ACEMMECPA1ACE2
SCHEMBL23859822 0.85 NPSR1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096514-B Polymerizable amino acid-based compounds and ophthalmic devices made therefrom 强生视力健公司 2025-06-17 CN claimed
EP-4165015-B9 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-11-27 EP claimed
EP-4165015-B1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-08-07 EP claimed
CN-114096514-A Amino acid based polymerizable compounds and ophthalmic devices made therefrom 强生视力健公司 2022-02-25 CN claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-20110311505-A1 Photosensitive Aminoacid-Monomer Linkage and Bioconjugation Applications in Life Sciences and Biotechnology Say, Ridvan (TR) 2011-12-22 US claimed
US-6583197-B1 Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent KABUSHIKI KAISHA SHOFU (JP) 2003-06-24 US claimed
WO-2000069394-A1 ONE-PART FLUORIDE RELEASING DENTAL MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-23 WO claimed
EP-4165015-B9 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-11-27 EP disclosed
EP-4165015-B1 AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM JOHNSON AND JOHNSON VISION CARE INC (US) 2024-08-07 EP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-20240199494-A1 ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF Kuraray Noritake Dental lnc. (JP) 2024-06-20 US disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
US-20240139078-A1 DENTAL FILLING KIT KURARAY NORITAKE DENTAL INC. (JP) 2024-05-02 US disclosed
EP-1066813-A2 Dental adhesive composition KABUSHIKI KAISHA SHOFU (JP) 2001-01-10 EP disclosed
WO-2000069394-A1 ONE-PART FLUORIDE RELEASING DENTAL MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-23 WO disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
US-5175254-A Solid phase peptide synthesis using a polyacrylic support in aqueous solution SOCIETE D'EXPANSION SCIENTIFQUE EXPANSIA (FR) 1992-12-29 US disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240139078-A1 DENTAL FILLING KIT DHX29, DHX35, DHX15 FOLH1 2113/4885NAALAD2 1089/4885ACE 4099/4885
US-20110311505-A1 Photosensitive Aminoacid-Monomer Linkage and Bioconjugation Applications in Life Sciences and Biotechnology BCAT1, BCAT2, AADAT FOLH1 2471/4885NAALAD2 100/4885ACE 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.