Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671866 | 0.92 | RAB9A (0.52) | RAB9ANPC1MAPTGAAKDM4E | |
| SCHEMBL6086455 | 0.88 | L3MBTL1 (0.50) | RAB9ANPC1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL6834291 | 0.82 | L3MBTL1 (0.54) | RAB9ANPC1MAPTGAAKDM4E | |
| SCHEMBL16482131 | 0.80 | IDO1 (0.49) | RAB9ANPC1MAPTGAAKDM4E | |
| SCHEMBL30338333 | 0.79 | CYP1A2 (0.50) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL28281773 | 0.79 | RAB9A (0.38) | RAB9ANPC1KDM4EALDH1A1POLB | |
| SCHEMBL995408 | 0.79 | CYP1A2 (0.50) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL23302623 | 0.78 | SMN1; SMN2 (0.47) | RAB9ANPC1MAPTGAAKDM4E | |
| SCHEMBL27788974 | 0.78 | MAPT (0.48) | RAB9AMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL27534068 | 0.77 | CHRNB2 (0.43) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339870-A1 | CINNAMIC AMIDE DERIVATIVE HAVING FXR ACTIVATING EFFECT, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT, AND METHOD FOR PREPARING THE SAME | KYUNGSUNG UNIVERSITY INDUSTRY COOPERATION FOUNDATION (KR) | 2023-10-26 | — | — | US | claimed |
| WO-2021085991-A1 | CINNAMIC AMIDE DERIVATIVE HAVING FXR ACTIVATING EFFECT, PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT, AND PREPARATION METHOD THEREFOR | 경성대학교 산학협력단 | 2021-05-06 | — | — | WO | disclosed |
| CN-108659007-A | A kind of preparation method of dicloxacillin sodium pillar-shaped crystal | 华北制药集团先泰药业有限公司 | 2018-10-16 | — | — | CN | disclosed |
| EP-2409985-A2 | Inhibitors de serine proteases, especially of the NS3 protease of the hepatitis C virus | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2314598-A1 | Inhibitors of Hepatitis C virus NS3 serine protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-27 | — | — | EP | disclosed |
| EP-0229369-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-3971776-A | MICROBIOCIDE | E. R. SQUIBB & SONS, INC. (US) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339870-A1 | CINNAMIC AMIDE DERIVATIVE HAVING FXR ACTIVATING EFFECT, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT, AND METHOD FOR PREPARING THE SAME | CEL, NR1H4, FXR1 | RAB9A 1432/4885NPC1 24/4885MAPT 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.