SCHEMBL10165220

SCHEMBL10165220

C=C(C)C(=O)Oc1cc(C(C)(C)O)cc(C(C)(O)C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.36
▸ HSD11B1 P28845 4/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12635204 0.96 ELANE (0.39) ELANEHSD11B1KMT2AATM
SCHEMBL15858784 0.90 ELANE (0.35) ELANEHSD11B1KMT2AATM
SCHEMBL19420421 0.90 ELANE (0.35) ELANEHSD11B1KMT2AATM
SCHEMBL12175978 0.90 ELANE (0.35) ELANEHSD11B1KMT2AATM
SCHEMBL21580265 0.89 ELANE (0.42) ELANEKMT2AATM
SCHEMBL25561467 0.88 ELANE (0.38) ELANEKMT2AATM
SCHEMBL2266773 0.82 ELANE (0.40) ELANEKMT2AATM
SCHEMBL15836489 0.81 HSD11B1 (0.49) ELANEHSD11B1KMT2AATM
SCHEMBL5004362 0.80 ELANE (0.42) ELANEKMT2AATM
SCHEMBL16843430 0.78 SMN1; SMN2 (0.36) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 — — US disclosed
US-10040879-B2 Fluoro-alcohol additives for orientation control of block copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-08-07 — — US disclosed
US-9999633-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-19 — — US disclosed
US-9987369-B2 Vitamin functionalized gel-forming block copolymers for biomedical applications INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-05 — — US disclosed
US-9982097-B2 Thin film self assembly of topcoat-free silicon-containing diblock copolymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 — — US disclosed
US-9974303-B2 Cationic polymers for antimicrobial applications and delivery of bioactive materials INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-22 — — US disclosed
US-20180117162-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-05-03 — — US disclosed
US-20180112033-A1 POLYESTER NANOGEL CORE STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-04-26 — — US disclosed
US-9951179-B2 Cyclic carbonate monomers and ring opened polycarbonates therefrom INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 — — US disclosed
US-9901649-B2 Block copolymers for therapeutic drug delivery INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-02-27 — — US disclosed
US-8226985-B2 Surface modified nanoparticles, methods of their preparation, and uses thereof for gene and drug delivery INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-24 — — US disclosed
US-20120178891-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF CENTRAL GLASS CO., LTD. (JP) 2012-07-12 — — US disclosed
US-20120178925-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-12 — — US disclosed
US-20120172603-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 — — US disclosed
US-20120172602-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 — — US disclosed
US-20120172559-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-07-05 — — US disclosed
US-8207351-B2 Cyclic carbonyl compounds with pendant carbonate groups, preparations thereof, and polymers therefrom INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-06-26 — — US disclosed
US-20110269917-A1 CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM CENTRAL GLASS CO., LTD. (JP) 2011-11-03 — — US disclosed
US-20110243848-A1 STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-10-06 — — US disclosed
US-20110182996-A1 SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2011-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172603-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA ELANE 717/4885HSD11B1 3762/4885KMT2A 4165/4885
US-20110243848-A1 STAR POLYMERS, METHODS OF PREPARATION THEREOF, AND USES THEREOF AS3MT, STARD7, MCM5 ELANE 3709/4885HSD11B1 4779/4885KMT2A 3888/4885
US-20120178925-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA ELANE 717/4885HSD11B1 3762/4885KMT2A 4165/4885
US-20110182996-A1 SURFACE MODIFIED NANOPARTICLES, METHODS OF THEIR PREPARATION, AND USES THEREOF FOR GENE AND DRUG DELIVERY ABCB7, CD63, ITGB3 ELANE 1237/4885HSD11B1 3985/4885KMT2A 3136/4885
US-20180117162-A1 VITAMIN FUNCTIONALIZED GEL-FORMING BLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS VDR, PROC, CYP24A1 ELANE 2196/4885HSD11B1 2106/4885KMT2A 4014/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS ELANE 512/4885HSD11B1 4653/4885KMT2A 4588/4885
US-20110269917-A1 CYCLIC CARBONYL COMPOUNDS WITH PENDANT CARBONATE GROUPS, PREPARATIONS THEREOF, AND POLYMERS THEREFROM NOTUM, PFAS, PCNA ELANE 2300/4885HSD11B1 2861/4885KMT2A 4170/4885
US-20120172602-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA ELANE 717/4885HSD11B1 3762/4885KMT2A 4165/4885
US-20180112033-A1 POLYESTER NANOGEL CORE STAR POLYMERS FOR DELIVERY OF THERAPEUTIC AGENTS STARD10, STARD7, ABCB7 ELANE 3367/4885HSD11B1 1424/4885KMT2A 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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