Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253082 | 0.92 | ADAMTS4 (0.46) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10162424 | 0.89 | MMP13 (0.47) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10162395 | 0.88 | ADAMTS4 (0.41) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10162223 | 0.85 | MMP13 (0.41) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL8256711 | 0.83 | ADAMTS4 (0.42) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10161698 | 0.82 | MMP13 (0.43) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10161671 | 0.82 | MMP13 (0.43) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10165950 | 0.82 | MMP13 (0.41) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL10161870 | 0.82 | MMP13 (0.67) | MMP13ADAMTS4MMP3ROCK2ROCK1 | |
| SCHEMBL8220206 | 0.82 | MMP13 (0.39) | MMP13ADAMTS4MMP3ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015920-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015920-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | MMP13, TIMP3, MMP3 | MMP13 1/4885ADAMTS4 38/4885MMP3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.