Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132686 | 0.78 | FKBP1A (0.35) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL18253358 | 0.77 | ALDH1A1 (0.35) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL18253360 | 0.76 | ALDH1A1 (0.35) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL6367523 | 0.74 | FKBP1A (0.34) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL132912 | 0.73 | CYP19A1 (0.39) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL12993041 | 0.73 | NPY1R (0.37) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL9945786 | 0.72 | HMGCR (0.37) | HMGCRALDH1A1MEN1KMT2A | |
| SCHEMBL3434651 | 0.70 | CYP19A1 (0.42) | HMGCRCYP3A4USP2ALDH1A1TSHR | |
| SCHEMBL17460664 | 0.70 | HMGCR (0.33) | HMGCRCHRM1SLCO1B1 | |
| SCHEMBL2735055 | 0.70 | FKBP1A (0.33) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124224-B2 | Antireflection laminate, polarizing plate and image display device | FUJIFILM CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |