Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353355 | 0.89 | KMT2A (0.36) | LMNAPOLBPKMKMT2AMEN1 | |
| SCHEMBL351633 | 0.83 | KMT2A (0.40) | LMNAPOLBPKMKMT2AMEN1 | |
| SCHEMBL10167555 | 0.82 | KCNQ3 (0.36) | POLBPKMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10167578 | 0.80 | L3MBTL1 (0.42) | LMNAPOLBPKMKMT2AMEN1 | |
| SCHEMBL352691 | 0.78 | KMT2A (0.39) | LMNAPOLBPKMKMT2AMEN1 | |
| SCHEMBL357050 | 0.75 | KDM4E (0.34) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10167556 | 0.72 | KMT2A (0.35) | LMNAPOLBPKMKMT2AMEN1 | |
| SCHEMBL353134 | 0.72 | HCRTR1 (0.39) | KMT2AMEN1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL358113 | 0.72 | KMT2A (0.40) | LMNAPOLBPKMKMT2AMEN1 | |
| SCHEMBL352456 | 0.71 | HCRTR1 (0.39) | KMT2AMEN1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |