Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.47 |
| ▸ | TUBB | P07437 | 8/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.47 |
| ▸ | SMO | Q99835 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425092 | 0.88 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10176211 | 0.88 | SMO (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10176208 | 0.77 | SMO (0.50) | SMOKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL10176182 | 0.76 | FLT3 (0.54) | CYP1A1KDM4EALDH1A1HPGDVCP | |
| SCHEMBL13814176 | 0.74 | SMO (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL424789 | 0.74 | SMO (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10176210 | 0.74 | RAB9A (0.56) | SMOKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL4333228 | 0.73 | CYP1A1 (0.58) | CYP1A1KDM4EALDH1A1HPGDAHR | |
| SCHEMBL10176213 | 0.72 | SMO (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13814178 | 0.72 | SMO (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
| US-20090142832-A1 | Indoles, Derivatives, and Analogs Thereof and Uses Therefor | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | TUBB, TUBB3, TUBB1 | TUBB4A 6/4885TUBB 1/4885TUBA3C 24/4885 |
| US-20090142832-A1 | Indoles, Derivatives, and Analogs Thereof and Uses Therefor | TUBB, TUBB1, TUBB6 | TUBB4A 10/4885TUBB 1/4885TUBA3C 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.