Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312347 | 0.88 | MLYCD (0.52) | MLYCDGPBAR1NOTUMEPHX2CLK1 | |
| SCHEMBL31073566 | 0.85 | MLYCD (0.56) | MLYCDGPBAR1NOTUMEPHX2HDAC8 | |
| SCHEMBL18046159 | 0.85 | MLYCD (0.52) | MLYCDGPBAR1NOTUMEPHX2TAS2R14 | |
| SCHEMBL13122963 | 0.84 | GPBAR1 (0.53) | GPBAR1ADCY8ADCY1TAS2R14KMT2A | |
| SCHEMBL20703207 | 0.84 | MLYCD (0.51) | MLYCDGPBAR1NOTUMHDAC8 | |
| SCHEMBL18374368 | 0.82 | MLYCD (0.52) | MLYCDGPBAR1NOTUMEPHX2CLK1 | |
| SCHEMBL16421209 | 0.82 | MLYCD (0.52) | MLYCDGPBAR1NOTUMEPHX2CLK1 | |
| SCHEMBL5367773 | 0.81 | MLYCD (0.51) | MLYCDGPBAR1NOTUMEPHX2CLK1 | |
| SCHEMBL31255266 | 0.81 | NOTUM (0.64) | MLYCDGPBAR1NOTUMEPHX2CLK1 | |
| SCHEMBL4843412 | 0.80 | MLYCD (0.49) | MLYCDCLK1DYRK1ADYRK1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-10-13 | — | — | US | disclosed |
| EP-2271639-A2 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer CropScience AG (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20100286173-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | US | disclosed |
| WO-2009090237-A2 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | QDPR, SIRT5, PDXK | MLYCD 614/4885GPBAR1 2299/4885NOTUM 2577/4885 |
| US-20100286173-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | HAAO, CYP51A1, HPD | MLYCD 1042/4885GPBAR1 4680/4885NOTUM 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.