Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 10/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10176339 | 0.74 | TSHR (0.35) | ALDH1A1TSHRPLA2G10HAO1IL1R1 | |
| SCHEMBL10176177 | 0.72 | CA12 (0.49) | ALDH1A1TSHRPLA2G10HAO1MAPT | |
| SCHEMBL10176353 | 0.70 | FLT3 (0.38) | ALDH1A1TSHRMAPT | |
| SCHEMBL10176337 | 0.65 | PDE4A (0.39) | — | |
| SCHEMBL10176489 | 0.65 | ALDH1A1 (0.48) | ALDH1A1TSHRPLA2G10 | |
| SCHEMBL16902648 | 0.64 | RORC (0.46) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL21507372 | 0.63 | ALDH1A1 (0.59) | ALDH1A1TSHRPLA2G10HAO1CYP19A1 | |
| SCHEMBL5208338 | 0.62 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10 | |
| SCHEMBL30194196 | 0.62 | ALDH1A1 (1.00) | ALDH1A1TSHRPLA2G10 | |
| SCHEMBL28236106 | 0.62 | TSHR (0.54) | ALDH1A1TSHRPLA2G10HAO1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022121-A1 | INDOLES, DERIVATIVES AND ANALOGS THEREOF AND USES THEREFOR | TUBB, TUBB3, TUBB1 | ALDH1A1 1001/4885TSHR 4545/4885PLA2G10 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.