SCHEMBL10178722

SCHEMBL10178722

CCC(C)c1cccc(COc2ccc(C(C)=O)cc2)c1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 16/20 0.64
MAOA P21397 4/20 0.62
MRGPRX4 Q96LA9 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PTPRC P08575 1/20 0.50
PTPN1 P18031 1/20 0.50
TP53 P04637 1/20 0.50
PKM P14618 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10178740 0.88 MRGPRX4 (0.57) MAOBMRGPRX4SMN1; SMN2ALDH1A1HTT
SCHEMBL10178734 0.84 MRGPRX4 (0.51) MAOBMRGPRX4SMN1; SMN2PTPRCPTPN1
SCHEMBL10178588 0.84 MAOB (0.64) MAOBMAOASMN1; SMN2ALDH1A1HTT
SCHEMBL14461904 0.84 MAOB (0.64) MAOBMAOASMN1; SMN2ALDH1A1HTT
SCHEMBL10178653 0.82 BCHE (0.53) MAOBMRGPRX4SMN1; SMN2
SCHEMBL10178751 0.80 FFAR1 (0.53) MAOBMRGPRX4
SCHEMBL10178709 0.80 FFAR1 (0.48) MRGPRX4
SCHEMBL15613835 0.79 MAOB (0.54) MAOBMAOAMRGPRX4SMN1; SMN2HTT
SCHEMBL10178559 0.79 MEN1 (0.48) MAOBMRGPRX4SMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL9545816 0.78 MAOB (1.00) MAOBMAOASMN1; SMN2ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124310-B2 Positive resist composition and pattern forming method using the same FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-20090087784-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed