Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181343 | 0.84 | PRMT5 (0.44) | PRMT5 | |
| SCHEMBL10179669 | 0.81 | KCNJ1 (0.38) | KCNJ1KCNH2GPR119ALDH1A1HPGD | |
| SCHEMBL10181213 | 0.80 | PRMT5 (0.40) | PRMT5 | |
| SCHEMBL10179268 | 0.80 | PRMT5 (0.41) | PRMT5GPR119 | |
| SCHEMBL10181211 | 0.80 | PRMT5 (0.40) | PRMT5 | |
| SCHEMBL1578058 | 0.78 | GPR119 (0.47) | KCNJ1KCNH2GPR119ALDH1A1HPGD | |
| SCHEMBL10181205 | 0.75 | ALDH1A1 (0.38) | KCNJ1KCNH2GPR119ALDH1A1HPGD | |
| SCHEMBL10179902 | 0.75 | ALDH1A1 (0.36) | KCNJ1KCNH2GPR119ALDH1A1HPGD | |
| SCHEMBL1577822 | 0.74 | GPR119 (0.53) | GPR119ALDH1A1HPGD | |
| SCHEMBL14141945 | 0.73 | ALDH1A1 (0.36) | KCNJ1KCNH2GPR119ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245344-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2012-09-27 | — | — | US | disclosed |
| EP-2474540-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245344-A1 | GPR119 AGONIST | GPR119, GPR4, GPR55 | PRMT5 1363/4885KCNJ1 789/4885KCNH2 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.