SCHEMBL10180431

SCHEMBL10180431

CCC(C)(C)c1cccc(S(=O)(=O)c2cccc(C(C)(C)CC)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.49
LMNA P02545 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
MAPK1 P28482 1/20 0.49
CASP3 P42574 1/20 0.49
ATM Q13315 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
HSD11B1 P28845 2/20 0.40
HTR6 P50406 3/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10179833 0.95 SMN1; SMN2 (0.49) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10181288 0.87 PSIP1 (0.48) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10179978 0.87 KIF11 (0.49) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL19518816 0.86 CA2 (0.53) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL13898726 0.86 SMN1; SMN2 (0.46) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL23731657 0.86 SMN1; SMN2 (0.45) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL29301827 0.83 NR3C2 (0.49) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10181261 0.83 LMNA (0.44) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10181117 0.82 NPC1 (0.43) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10181257 0.80 NPC1 (0.45) SMN1; SMN2LMNANPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed
CN-102484281-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2012-05-30 CN disclosed