SCHEMBL10179833

SCHEMBL10179833

CCC(C)(C)c1cccc(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.49
LMNA P02545 4/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPK1 P28482 1/20 0.49
CASP3 P42574 1/20 0.49
ATM Q13315 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
HTR6 P50406 3/20 0.47
HSD11B1 P28845 2/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 2/20 0.44
TSHR P16473 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10180431 0.95 SMN1; SMN2 (0.49) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10180029 0.84 HSD11B1 (0.56) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10179978 0.83 KIF11 (0.49) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10181288 0.83 PSIP1 (0.48) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL10181725 0.82 HTR6 (0.54) SMN1; SMN2LMNANPC1RAB9ACASP3
SCHEMBL10180926 0.81 LMNA (0.44) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL13898726 0.81 SMN1; SMN2 (0.46) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL19518816 0.81 CA2 (0.53) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL23731657 0.81 SMN1; SMN2 (0.45) SMN1; SMN2LMNANPC1RAB9AMAPK1
SCHEMBL11289826 0.79 NR3C2 (0.51) SMN1; SMN2LMNANPC1RAB9AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed