Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311263 | 0.89 | ALDH1A1 (0.59) | MTNR1AMTNR1BEPHX1ALDH1A1MAPT | |
| SCHEMBL9407494 | 0.84 | GAA (0.58) | MTNR1AMTNR1BEPHX1CTSKALDH1A1 | |
| SCHEMBL10126817 | 0.84 | MAPT (0.61) | MTNR1AMTNR1BCTSKMAPTLMNA | |
| SCHEMBL7203913 | 0.83 | MALT1 (0.59) | EPHX1CTSKGAAMEN1KMT2A | |
| SCHEMBL11843114 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BEPHX1ALDH1A1MAPT | |
| SCHEMBL10154474 | 0.80 | MTNR1A (0.78) | MTNR1AMTNR1BALDH1A1RAB9ANPC1 | |
| SCHEMBL3565228 | 0.80 | EPHX1 (0.54) | MTNR1AMTNR1BEPHX1CTSKALDH1A1 | |
| SCHEMBL14515852 | 0.80 | LMNA (0.64) | ALDH1A1MAPTLMNAGAAHTT | |
| SCHEMBL9407487 | 0.78 | CTSK (0.46) | EPHX1CTSKALDH1A1MAPTLMNA | |
| SCHEMBL14065544 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412711-A1 | INDAZOLEPROPIONIC ACID AMIDE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-02-01 | — | — | EP | disclosed |