Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018124 | 0.88 | CA2 (0.54) | CA2CA1CA12CA7CA13 | |
| SCHEMBL30655866 | 0.85 | CA2 (0.53) | CA2CA1CA12CA7CA13 | |
| SCHEMBL51274 | 0.82 | GAA (0.54) | CA2CA1CA12CA7CA13 | |
| SCHEMBL8637757 | 0.82 | CA2 (0.61) | CA2CA1CA12CA7CA13 | |
| SCHEMBL10872171 | 0.82 | HPGD (0.57) | CA2CA1CA12CA7CA13 | |
| SCHEMBL1017821 | 0.82 | HTT (0.51) | CA2CA1CA12CA7CA13 | |
| SCHEMBL2914385 | 0.82 | TSHR (0.48) | CA2CA1CA12CA7TSHR | |
| SCHEMBL12365457 | 0.82 | ALDH1A1 (0.53) | CA2CA1CA12CA7TSHR | |
| Hydrochloric Acid SCHEMBL28033163 | 0.80 | TSHR (0.46) | CA2CA1CA12CA7TSHR | |
| SCHEMBL10876734 | 0.79 | PLA2G4B (0.53) | TSHRTP53SMN1; SMN2PLA2G2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136369-A1 | SAFETY-CATCH LINKERS FOR SOLID PHASE PEPTIDE SYNTHESIS | AAPPTec, LLC (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250197441-A1 | Safety-Catch Linkers for Solid Phase Peptide Synthesis | AAPPTec, LLC (US) | 2025-06-19 | — | — | US | disclosed |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| US-20210070707-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2021-03-11 | — | — | US | disclosed |
| US-20200190030-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2020-06-18 | — | — | US | disclosed |
| US-20180258043-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2018-09-13 | — | — | US | disclosed |
| US-20180029984-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2018-02-01 | — | — | US | disclosed |
| US-9790183-B2 | Pyridyl inhibitors of hedgehog signalling | GENENTECH, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170015627-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| WO-2009053999-A2 | SULFOXIMINE DERIVATIVES AS FACTOR XA INHIBITORS | CADILA HEALTHCARE LIMITED (IN) | 2009-04-30 | — | — | WO | disclosed |
| EP-1789390-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | Genentech, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | CURIS ROYALTY LLC | 2006-03-23 | — | — | US | disclosed |
| WO-2006028958-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20040171079-A1 | Combinatorial active compound synthesis and its intermediates | HAAF KLAUS (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20030158443-A1 | Combinatorial active compound synthesis and its intermediates | HAAF KLAUS (DE) | 2003-08-21 | — | — | US | disclosed |
| EP-0837056-B1 | Combinatorial reagent synthesis and intermediates therefor | BAYER CROPSCIENCE GMBH (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020128383-A1 | COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES | HOECHST SCHERING AGREVO GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
| EP-0837056-A2 | Combinatorial reagent synthesis and intermediates therefor | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
| US-4922014-A | Process for the preparation of oxethylmercaptobenzaldehydes and their oxidation products | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197441-A1 | Safety-Catch Linkers for Solid Phase Peptide Synthesis | PNISR, SPPL2B, VIP | CA2 3985/4885CA1 1956/4885CA12 2697/4885 |
| US-20200190030-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
| US-20230265054-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
| US-20240116872-A1 | PYRIDYL INHIBITORS FOR HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3954/4885CA1 4482/4885CA12 4756/4885 |
| US-20180029984-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
| US-20040171079-A1 | Combinatorial active compound synthesis and its intermediates | NCL, POLR2E, NOC2L | CA2 2640/4885CA1 1753/4885CA12 2489/4885 |
| US-20210070707-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
| US-20030158443-A1 | Combinatorial active compound synthesis and its intermediates | NCL, POLR2E, COASY | CA2 2869/4885CA1 1935/4885CA12 2657/4885 |
| US-20180258043-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
| US-20170015627-A1 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
| US-20020128383-A1 | COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES | NCL, POLR2E, NOC2L | CA2 2429/4885CA1 1586/4885CA12 2298/4885 |
| US-20060063779-A1 | Pyridyl inhibitors of hedgehog signalling | SHH, GLI1, SMO | CA2 3856/4885CA1 4396/4885CA12 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.