Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10184034 | 0.93 | CCKBR (0.36) | CCKBROPRM1OPRK1OPRL1AGTR2 | |
| SCHEMBL10183321 | 0.88 | OPRM1 (0.37) | CCKBROPRM1OPRK1OPRL1AGTR2 | |
| SCHEMBL10184038 | 0.87 | KMT2A (0.36) | CCKBRITGB1ITGA4IDH1CYP2D6 | |
| SCHEMBL10183783 | 0.82 | OPRM1 (0.39) | CCKBROPRM1OPRK1OPRL1AGTR2 | |
| SCHEMBL10183299 | 0.82 | OPRM1 (0.40) | CCKBROPRM1OPRK1OPRL1AGTR2 | |
| SCHEMBL10185587 | 0.82 | TRPM8 (0.41) | CCKBROPRM1OPRK1OPRL1 | |
| SCHEMBL10183320 | 0.82 | AGTR2 (0.40) | CCKBROPRM1OPRK1OPRL1AGTR2 | |
| SCHEMBL10185957 | 0.82 | TSHR (0.43) | OPRM1OPRK1OPRL1IDH1 | |
| SCHEMBL10183319 | 0.81 | MEN1 (0.43) | CCKBROPRM1OPRK1OPRL1AGTR2 | |
| SCHEMBL10183337 | 0.81 | OPRM1 (0.39) | CCKBROPRM1OPRK1OPRL1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009678-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |