Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10185230 | 0.91 | PDE4A (0.45) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL10185609 | 0.90 | PDE4A (0.44) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL10186216 | 0.89 | PDE4A (0.48) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL10186450 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL10186490 | 0.88 | ENPP2 (0.42) | DGAT1ENPP2PTGDR2RXFP1 | |
| SCHEMBL10184421 | 0.87 | DGAT1 (0.38) | PDE4APDE4BPDE4CPDE4DDGAT1 | |
| SCHEMBL10185212 | 0.87 | PDE4A (0.47) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL10186226 | 0.86 | PDE4D (0.38) | PDE4APDE4BPDE4CPDE4DDGAT1 | |
| SCHEMBL10185571 | 0.86 | RXFP1 (0.45) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL10185022 | 0.85 | FAAH (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | ALDH1A1 963/4885SMN1; SMN2 4464/4885PDE4A 1520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.