Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 3/20 | 0.37 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.36 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10184505 | 0.90 | HRH3 (0.43) | HRH3DGAT1SOAT1MMP12ACSL1 | |
| SCHEMBL10186478 | 0.86 | HRH3 (0.40) | HRH3DGAT1SOAT1MMP12ACSL1 | |
| SCHEMBL10184394 | 0.85 | HRH3 (0.41) | HRH3DGAT1SOAT1MMP12ACSL1 | |
| SCHEMBL10185427 | 0.84 | DGAT1 (0.49) | HRH3DGAT1 | |
| SCHEMBL10186471 | 0.84 | DGAT1 (0.48) | HRH3DGAT1SOAT1 | |
| SCHEMBL10186184 | 0.83 | ALDH1A1 (0.44) | HRH3DGAT1SOAT1RXFP1 | |
| SCHEMBL10186189 | 0.83 | HRH3 (0.42) | HRH3DGAT1SOAT1MMP12ACSL1 | |
| SCHEMBL10185434 | 0.83 | RAB9A (0.44) | HRH3DGAT1 | |
| SCHEMBL10185735 | 0.83 | L3MBTL1 (0.49) | HRH3DGAT1SOAT1MMP12ACSL1 | |
| SCHEMBL10184525 | 0.83 | DGAT1 (0.40) | HRH3DGAT1SOAT1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | HRH3 2422/4885DGAT1 1/4885SOAT1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.