Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10185728 | 0.90 | KMT2A (0.49) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL10185135 | 0.86 | RAB9A (0.48) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL662809 | 0.85 | RXFP1 (0.56) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL662810 | 0.85 | RXFP1 (0.56) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL10185783 | 0.85 | RXFP1 (0.56) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL10186252 | 0.84 | LMNA (0.47) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL10185714 | 0.84 | RAB9A (0.47) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL10185773 | 0.83 | L3MBTL1 (0.51) | HTTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10185078 | 0.82 | RAB9A (0.48) | KMT2ARXFP1MEN1HTTRAB9A | |
| SCHEMBL10186238 | 0.81 | RAB9A (0.46) | KMT2AMEN1RAB9AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | KMT2A 441/4885RXFP1 3304/4885MEN1 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.