Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | IL6 | P05231 | 5/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 3/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.32 |
| ▸ | MERTK | Q12866 | 3/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 3/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251206 | 0.90 | ALDH1A1 (0.35) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL10186691 | 0.83 | ALDH1A1 (0.43) | CNR1CNR2ALDH1A1TSHRPOLB | |
| SCHEMBL8234940 | 0.81 | CNR1 (0.40) | CNR1CNR2IL6TLR7ALDH1A1 | |
| SCHEMBL10186705 | 0.79 | SIGMAR1 (0.40) | TLR7ALDH1A1POLBLMNAGAA | |
| SCHEMBL10186702 | 0.78 | ALDH1A1 (0.40) | CNR1CNR2IL6TLR7ALDH1A1 | |
| SCHEMBL10186694 | 0.77 | CNR1 (0.34) | CNR1CNR2IL6TLR7ALDH1A1 | |
| SCHEMBL664743 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL88993 | 0.75 | ALDH1A1 (0.40) | IL6TLR7ALDH1A1TSHRPOLB | |
| SCHEMBL663467 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TSHRPOLBL3MBTL1MEN1 | |
| SCHEMBL8250680 | 0.70 | SIGMAR1 (0.38) | ALDH1A1POLBGAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046293-A1 | RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046293-A1 | RENIN INHIBITORS | REN, ACE, AGTR1 | CNR1 3491/4885CNR2 3812/4885IL6 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.