Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19963006 | 0.80 | EP300 (0.41) | EP300CNR2KDM1ACCNA2CDK2 | |
| SCHEMBL9966863 | 0.78 | KDM1A (0.40) | EP300CNR2KDM1ACCNA2CDK2 | |
| SCHEMBL10187309 | 0.75 | ALDH1A1 (0.39) | DHFR | |
| SCHEMBL20772826 | 0.74 | CCNA2 (0.41) | EP300CNR2KDM1ACCNA2CDK2 | |
| SCHEMBL10485526 | 0.74 | CCNA2 (0.44) | EP300CNR2CCNA2CDK2CCNA1 | |
| SCHEMBL5280 | 0.72 | HTR7 (0.50) | EP300CNR2KDM1ACCNA2CDK2 | |
| SCHEMBL2728360 | 0.72 | MCHR1 (0.50) | EP300CNR2KDM1ACCNA2CDK2 | |
| SCHEMBL22834474 | 0.72 | NUDT1 (0.53) | EP300CCNA2CDK2CCNA1LRRK2 | |
| SCHEMBL30350618 | 0.72 | HTR7 (0.50) | EP300CNR2KDM1ACCNA2CDK2 | |
| SCHEMBL20772824 | 0.72 | CDK2 (0.39) | EP300CNR2KDM1ACCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |